As part of the trusted equine pain and sedation portfolio from zoetis, ketofen is safe and effective against equine pain and. Plumbs veterinary drug handbook edition 8 by donald c. An interaction is when a substance changes the way a drug works. This medication is a nonsteroidal antiinflammatory drug nsaid. Ketofen, anafen, orudis, rhovail, rhodis, oruvail is a nonsteroidal antiinflammatory drug nsaid used to treat pain and inflammation, as well as to control fever in companion animals only. Safety and efficacy of reduced dosage ketoprofen with or without. Providing referenced dosing recommendations in each monograph, this book offers doses for a wide range of species, including dogs, cats, exotic animals, and farm animals, in a single resource. Feb 21, 2006 orudis ketoprofen is a nonsteroidal antiinflammatory drug used to treat pain or inflammation caused by arthritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Donald c plumb now in a fully updated seventh edition, this handbook is a source of drug information relevant for animals. R2 under the animal medicinal drug use clarification act amduca amendments to the food, drug, and cosmetic act, a nonsteroidal antiinflammatory drug that is labeled for use in foodproducing animals would be preferred over this product for use in those species. Ketoprofen is an nsaid and is used for treatment of moderate pain and inflammation.
Ketoprofen fda orange book approved drug product list. Veterinary anesthesia drug quick reference 1st edition. Bsava small animal formulary, part b exotic pets pdf. Handbook of veterinary pharmacology second edition is a clear and concise guide to pharmacology concepts and commonly used veterinary drugs. Many veterinary drugs have more than one name and, therefore, the same drug may be listed more than once. This formulary provides the readers useful information like, indications, dosage, contraindications and pharmaceutical precautions etc.
However, animal reproduction studies are not always predictive of human response. When ketoprofen is administered with food, its total bioavailability auc is not altered. The drug itself is also approved for use in humans, although it appears under other brand names such as orudis and actron. Providing referenced dosing recommendations in each monograph, this book offers doses for a. The product is an fdaapproved nonnarcotic, nonsteroidal antiinflammatory agent with analgesic and antipyretic properties. Ketoprofen v is approved for use in horses, swine and cattle with. Veterinary drug handbookclient information edition permission to photocopy for individual clients granted by gigi davidson and donald c. Ketoprofen is mostcommonly prescribed for musculoskeletal pain from soft tissue injury, osteoarthritis, or other bone and joint problems. Cautions federal law restricts this drug to use by or on the order of a licensed veterinarian.
Your vet erinarian may want to perform periodic liver function tests to show that your animals liver is working properly. List of maximum residue limits mrls for veterinary drugs. A listing of common veterinary drug uses for live export cattle. Mean plasma concentrations of ketoprofen in cattle following intramuscular injection of kelaprofen 100 mgml and the reference veterinary. Ketoprofen is used in both human and in veterinary medicine. The present study was planned to assess safety of ketoprofen 3 mg. Ketoprofen works by reducing hormones that cause inflammation and pain in the body.
Do not use in a horse if it has previously shown hypersensitivity to ketoprofen. Ketofen, anafen, orudis, rhovail, rhodis, oruvail is a nonsteroidal antiinflammatory drug nsaid used to treat pain and. Browse pdr s full list of drug information alphabetically by choosing the first letter of the drug you are tying to locate. Vultures feeding on the carcasses of recently treated livestock suffer acute kidney failure within days of exposure.
It also reduces pain, swelling, and joint stiffness from arthritis. They work by reducing the levels of prostaglandins, chemicals produced by the body that are responsible for. Kelaprofen 100 mgml duggan veterinary supplies ltd. Readily find dosing information for the drugs you prescribe every day with quick, easy access to the most up. Side effects of orudis ketoprofen, warnings, uses rxlist. Ketoprofen side effects, dosage, interactions drugs. This pocket reference contains anesthetic drugs, as well as those used perioperatively, descriptions and dosing information in commonly anesthetized species, and the various routes of administration commonly used in the practice of clinical veterinary anesthesia. The present study focuses on ketoprofen, which is used frequently as an analgesic in rodent surgery. Following the first edition of national veterinary drug formulary nvdf during 2011, second edition of nvdf is produced for the essential veterinary drugs lists evdl. Now in a fully updated seventh edition, plumbs veterinary drug handbook remains the most complete source of drug information relevant for animals available. Dec 11, 2014 ketoprofen and ketorolac are contraindicated in patients with active peptic ulcer, or with any history of gastrointestinal bleeding, ulceration, or perforation. Nonsteroidal antiinflammatory drugs merck veterinary manual.
Persons with disabilities having problems accessing the pdf files below may call 301 7963634 for assistance. Inn international nonproprietary name ban british approved name usan united states adopted name. List of maximum residue limits mrls for veterinary drugs in foods pdf version 337 k this list of mrls for veterinary drugs in foods sets out the level of residue that could safely remain in the tissue or food product derived from a foodproducing animal that has been treated with a veterinary drug. Ketoprofen is a nonsteroidal antiinflammatory drug nsaid and cyclooxygenase inhibitor. Favorites subscribe to favorite the drugs you use most often for quick access. Saunders handbook of veterinary drugs, 4th edition includes entries for 550 drugs, with convenient appendices summarizing clinically relevant information at a glance. Ketoprofen oral capsule is available as a generic drug. The medication is effective in reducing pain, inflammation, and joint swelling associated with different forms of arthritis and painful conditions. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and. Because ketoprofen is a nonselective nonsteroidal antiinflammatory drug that can damage the gastrointestinal tract, the putative diagnosis for these morbidities and mortalities was gastrointestinal toxicity caused by ketoprofen 5 mgkg. Veterinarians typically prescribe ketofen to aid in postoperative treatment or to relieve symptoms associated with arthritis, but it is a versatile drug that has a variety of. Ketoprofen oral capsule can interact with other medications, vitamins, or herbs you may be taking. Ketoprofen is one of the propionic acid class of nonsteroidal antiinflammatory drugs nsaid with analgesic and antipyretic effects. Other members of this class include ibuprofen, indomethacin, naproxen and many others.
It is a potent analgesic, antipyretic, and antiinflammatory. The data should not be regarded as absolute for every horse to which these substances are administered, nor does it apply to routes of administration or dosages other than those specified. It has a halflife in most animals of less than 2 hours, but it has a duration of action for up to 24 hours. Use of meloxicam or ketoprofen for piglet pain control. Other related drugs in this class include aspirin, ibuprofen and naproxen. Ketoprofen is not labeled for use in foodproducing animals in the u. We will be having several blog posts on how to do different types of calculations. Ketoprofen v is recommended for the alleviation of inflammation and pain associated with musculoskeletal disorders. A listing of common veterinary drug uses for live export sheep and goats. Ketoprofen v, presented in 100ml and 250ml vials, is a nonsteroidal antiinflammatory agent possessing antiinflammatory, analgesic and antipyretic properties. Ketoprofen, commonly known as ketofen, is used to arthritis pain, inflammation, and other musculoskeletal disorders in dogs and cats. Ketoprofen is an oral drug that belongs to a class of drugs called nonsteroidal antiinflammatory drugs.
Ketofen for cats veterinary medical information for dogs. Ketoprofen is a propionic acid derivate and nonsteroidal antiinflammatory drug nsaid with antiinflammatory, analgesic and antipyretic effects. Ketoprofen is one of the propionic acid class of nonsteroidal antiinflammatory drugs nsaid. The generic animal drug and patent restoration act requires that each sponsor of an approved animal drug must submit to the fda certain information regarding patents held for the animal drug or. Recent publications include portions of the pill book guide to medication for your dog and cat, and most recently understanding equine medications published. Experiments have found ketoprofen, like diclofenac, is a veterinary drug causing lethal. Explains the medication ketoprofen nexcede, orudis, oruvail, actron are all discontinued brands, a drug used for the treatment of inflammation and pain caused by rheumatoid arthritis and osteoarthritis, as well as soft tissue injuries, such as tendinitis and bursitis. Kelaprofen 100 mgml proved to be bioequivalent in horses, cattle and pigs with the reference veterinary medicine containing ketoprofen1. Ketoprofen is a nonsteroidal antiinflammatory agent possessing antiinflammatory, analgesic and antipyretic properties. Ketoprofen is a member of the nonsteroidal antiinflammatory drugs drug class and is commonly used for back pain, fever, frozen shoulder, and others. Many veterinary drugs have more than one name and, therefore, the same drug may be listed more than once abbreviations are used in the list as follows. Papich dvm, ms, dacvcp, in saunders handbook of veterinary drugs fourth edition, 2016 indications and clinical uses ketoprofen is an nsaid and is used for treatment of moderate pain and inflammation. New to this edition are 25 new drug monographs and easy access to drug content on any mobile device.
Ketoprofen should be stored in a tight, light re sistant, childproof container away from all chil dren and other household pets. List of approved drug products containing ketoprofen in the fda orange book on. Book bsava small animal formulary, part b exotic pets published in 2015 and the writer of the veterinary science medical book anna meredith veterinary books free download ninth edition of the bsava small animal formulary, where exotic pets have their own dedicated section that includes pet fish and amphibians for the first time. Ketoprofen belongs to the propionic acid subclass of carboxylic acid derivative nonsteroidal antiinflammatory drugs, which also includes ibuprofen, naproxen and fenoprofen. The eighth updated edition of plumbs veterinary drug handbook is a must reference for veterinarians and not only updates all of the monographs, but adds over forty new systemic drugs, identifies dosages by their usa label status, adds two new appendices on multi drug sensitivity in dogs and common drug store toxins, and expands monographs. This formulary is intended to aid the professionals and paraprofessionals in the veterinary field for guiding on the usage of the essential drugs in their day to day routine of treatment of animals. Nonsteroidal antiinflammatory drugs nsaids, such as meloxicam mel. Ketofen, a brand name of the drug ketoprofen, is an antiinflammatory used veterinary medicine. Ketoprofen is a type of nonsteroidal antiinflammatory drug nsaid that is used for general pain relief and to treat symptoms of arthritis. The results of these experiments had indicated that the drug ketoprofen is a safe and effective nsaid.
This information is based on a series of studies in which each drug was administered to a limited number of horses. Experiments have found ketoprofen, like diclofenac, is a veterinary drug causing lethal effects in redheaded vultures. This valuable reference is designed for quick access to clinically relevant anesthetic agents and techniques. The veterinary drugs directorate vdd has approved ketoprofen v ketoprofen injection, 100mgml in canada, according to manufacturer modern veterinary therapeutics. These drugs are used for the management of mild to moderate pain, fever, and inflammation. Nov 09, 2018 ketoprofen is a nonsteroidal antiinflammatory drug nsaid. See what others have said about ketoprofen, including the effectiveness, ease of use and side effects. It was patented in 1967 and approved for medical use in 1980. Jun 01, 2019 ketoprofen is 99% bound to plasma proteins, mainly to albumin.
Published reports have established the 5mgkg dose as safe and effective for rats. Ketofen ketoprofen sterile solution is a nonsteroidal antiinflammatory with analgesic and antipyretic properties. Subscribe to plumbs veterinary drugs to create and save personal notes for every drug you use. We want you to know how to calculate pet drug dosage. Commonly used drugs the board exam places a big emphasis on pharmacology. Experiments have found ketoprofen, like diclofenac, is a veterinary drug causing lethal effects in redheaded vulture s. Ketoprofen is a nonsteroidal antiinflammatory drug nsaid. Ketoprofen is a non steroidal antiinflammatory drug n said used for its antiinflammatory, analgesic and antipyretic properties in veterinary medicine. Contraindications there are no known contraindications to this drug when used as directed.
Ketoprofen inhibits the activity of the enzymes cyclooxygenase i and ii, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. Find patient medical information for ketoprofen oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Ketoprofen is used to relieve pain from various conditions. Ketoprofen belongs to a general class of drugs known as nonsteroidal antiinflammatory drugs nsaids. The following powerpage lists commonly used drugs in veterinary medicine with their classification and important information related to the drugs. Ketoprofen prescription drug information, interactions. Ketoprofen prices, coupons and patient assistance programs.
This article lists veterinary pharmaceutical drugs alphabetically by name. Ketoprofen orudis, a highly potent and safe nonsteroidal antiinflammatory drug of the propionic acid derivative group, was synthesized in france by rhonepoulenc chemists in 1967, 3 years after the prototype ibuprofen. Based on the general method for assessing the health risks of drug residues in water intended for human consumption that it proposed in 20, anses issued a formal internal request to assess the health risks of ketoprofen. Many drugs are commonly prescribed for off label use in veterinary medicine. This ketoprofen price guide is based on using the drugs. Absorption ketoprofen is rapidly and wellabsorbed, with peak plasma levels occurring within 0. Orudis ketoprofen may treat, side effects, dosage, drug interactions. Find specific details on this topic and related topics from the merck vet manual. Approved drug products containing ketoprofen listed in the fda orange book. Ketofen ketoprofen sterile solution patterson veterinary. Jul 27, 2017 in 2005, wyeth pharmaceuticals, the manufacturer of orudis kt, an overthecounter nonsteroidal antiinflammatory drug nsaid, informed the fda that it was discontinuing the manufacture of the 12. Ketoprofen is a non steroidal antiinflammatory drug nsaid used for its.
A description of best practice use of veterinary drugs and chemicals storage, record keeping, offlabel use, inventory control, disposal of unwanted drugs and the like. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Orudis kt was in the same class as other nsaids, like prescriptionstrength celebrex, bextra and vioxx. Five healthy dogs receiving standarddosage ketoprofen 2 mgkg sc, then. Providing a succinct overview of veterinary pharmacology, this book presents information in a userfriendly outline format to allow quick access to practical drug information. In these instances, follow your veterinarians directions and cautions very carefully as their direction may be significantly different from those on the label. Papich dvm, ms, dacvcp, in saunders handbook of veterinary drugs fourth edition, 2016. Handbook of veterinary pharmacology second edition. Ketoprofen ktp, is a powerful novel nonsteroidal anti inflammatory drug nsaid, approved for human and veterinary use in more than 70 countries including pakistan. The fastest drug reference for anyone in veterinary practice. Learn about the veterinary topic of nonsteroidal antiinflammatory drugs. It acts by inhibiting the bodys production of prostaglandin. Overview of ketoprofen ketofen for canines and felines. The brand name orudis is no longer available in the u.